Dean Appling, Ph.D., a leading researcher in biochemistry, will present a talk titled “Folic acid and Neural Tube Defects: Mitochondrial Formate Production in Mammalian Development” as part of the on-going speaker series in the Department of Nutritional Sciences.
Appling holds the Lester J. Reed Professorship in Biochemistry at The University of Texas at Austin. Appling’s research focuses on the compartments, like mitochondria and nuclei, found in eukaryotic cells. Although each of these compartments exhibits a distinct set of metabolic processes, they must all communicate with each other for the cell to function properly. Understanding how these processes are organized and controlled represents the next frontier in the study of metabolism. His research is focused on folate-mediated one-carbon metabolism. This set of pathways is found in all cells and organisms, is central to fundamental processes such as nucleic acid and protein synthesis, and occurs in multiple compartments.
The Nutritional Sciences speaker series is open to the public and all are invited to attend.